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Risk of colorectal adenomas and cancer in monoallelic carriers of MUTYH pathogenic variants: a single-centre experience

PURPOSE: The carrier frequency of MUTYH pathogenic variants in the population may be as high as one in 45. Some studies have found an increased risk of colorectal cancer (CRC) in monoallelic carriers of MUTYH pathogenic variants, but the role of early surveillance colonoscopy is not conclusive. This...

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Detalles Bibliográficos
Autores principales: Patel, R., McGinty, P., Cuthill, V., Hawkins, M., Clark, S. K., Latchford, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426294/
https://www.ncbi.nlm.nih.gov/pubmed/34244858
http://dx.doi.org/10.1007/s00384-021-03983-x