Cargando…
Risk of colorectal adenomas and cancer in monoallelic carriers of MUTYH pathogenic variants: a single-centre experience
PURPOSE: The carrier frequency of MUTYH pathogenic variants in the population may be as high as one in 45. Some studies have found an increased risk of colorectal cancer (CRC) in monoallelic carriers of MUTYH pathogenic variants, but the role of early surveillance colonoscopy is not conclusive. This...
Autores principales: | Patel, R., McGinty, P., Cuthill, V., Hawkins, M., Clark, S. K., Latchford, A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426294/ https://www.ncbi.nlm.nih.gov/pubmed/34244858 http://dx.doi.org/10.1007/s00384-021-03983-x |
Ejemplares similares
-
Risks of cancers for carriers of monoallelic MUTYH mutation with a family history of colorectal cancer
por: Win, Aung K, et al.
Publicado: (2011) -
Monoallelic deleterious MUTYH mutations generate colorectal cancer: A case report
por: Zhao, Bei, et al.
Publicado: (2023) -
Filling the gap: A thorough investigation for the genetic diagnosis of unsolved polyposis patients with monoallelic MUTYH pathogenic variants
por: Dell’Elice, Anastasia, et al.
Publicado: (2021) -
Multiple neoplasia in a patient with Gitelman syndrome harboring germline monoallelic MUTYH mutation
por: Chan, Jason Yongsheng, et al.
Publicado: (2020) -
Investigation of pathogenic mechanisms in multiple colorectal adenoma patients without germline APC or MYH/MUTYH mutations
por: Thirlwell, C, et al.
Publicado: (2007)