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Cytotoxic and radiosensitising effects of a novel thioredoxin reductase inhibitor in breast cancer

Radiotherapy is an effective treatment modality for breast cancer but, unfortunately, not all patients respond fully with a significant number experiencing local recurrences. Overexpression of thioredoxin and thioredoxin reductase has been reported to cause multidrug and radiation resistance - their...

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Detalles Bibliográficos
Autores principales: Abdullah, Nurul A, Inman, Martyn, Moody, Christopher J., Storr, Sarah J, Martin, Stewart G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426295/
https://www.ncbi.nlm.nih.gov/pubmed/33768386
http://dx.doi.org/10.1007/s10637-021-01106-5