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Cytotoxic and radiosensitising effects of a novel thioredoxin reductase inhibitor in breast cancer
Radiotherapy is an effective treatment modality for breast cancer but, unfortunately, not all patients respond fully with a significant number experiencing local recurrences. Overexpression of thioredoxin and thioredoxin reductase has been reported to cause multidrug and radiation resistance - their...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426295/ https://www.ncbi.nlm.nih.gov/pubmed/33768386 http://dx.doi.org/10.1007/s10637-021-01106-5 |