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Identification of a specific surface epitope of OmpC for Escherichia coli O157:H7 with protein topology facilitated affinity mass spectrometry

ABSTRACT: The goal of this work was to identify the target protein and epitope of a previously reported Escherichia coli O157:H7 (ECO157)–specific monoclonal antibody (mAb) 2G12. mAb 2G12 has shown high specificity for the recovery and detection of ECO157. To achieve this goal, the target protein wa...

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Detalles Bibliográficos
Autores principales: Wang, Wenbin, Zhou, Xinyue, Sang, Yunong, Liang, Xiaxia, Liu, Jianxin, Pan, Saikun, Wang, Luxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426304/
https://www.ncbi.nlm.nih.gov/pubmed/34432131
http://dx.doi.org/10.1007/s00253-021-11511-8