Intron retention-induced neoantigen load correlates with unfavorable prognosis in multiple myeloma

Neoantigen peptides arising from genetic alterations may serve as targets for personalized cancer vaccines and as positive predictors of response to immune checkpoint therapy. Mutations in genes regulating RNA splicing are common in hematological malignancies leading to dysregulated splicing and int...

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Detalles Bibliográficos
Autores principales: Dong, Chuanpeng, Cesarano, Annamaria, Bombaci, Giuseppe, Reiter, Jill L., Yu, Christina Y., Wang, Yue, Jiang, Zhaoyang, Zaid, Mohammad Abu, Huang, Kun, Lu, Xiongbin, Walker, Brian A., Perna, Fabiana, Liu, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426332/
https://www.ncbi.nlm.nih.gov/pubmed/34504297
http://dx.doi.org/10.1038/s41388-021-02005-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426332/
https://www.ncbi.nlm.nih.gov/pubmed/34504297
http://dx.doi.org/10.1038/s41388-021-02005-y

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