Use of a small molecule integrin activator as a systemically administered vaccine adjuvant in controlling Chagas disease

The development of suitable safe adjuvants to enhance appropriate antigen-driven immune responses remains a challenge. Here we describe the adjuvant properties of a small molecule activator of the integrins αLβ2 and α4β1, named 7HP349, which can be safely delivered systemically independent of antige...

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Detalles Bibliográficos
Autores principales: Lokugamage, Nandadeva, Chowdhury, Imran H., Biediger, Ronald J., Market, Robert V., Khounlo, Sayadeth, Warier, Navin D., Hwang, Shen-An, Actor, Jeffrey K., Woodside, Darren G., Marathi, Upendra, Vanderslice, Peter, Garg, Nisha Jain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426359/
https://www.ncbi.nlm.nih.gov/pubmed/34497271
http://dx.doi.org/10.1038/s41541-021-00378-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426359/
https://www.ncbi.nlm.nih.gov/pubmed/34497271
http://dx.doi.org/10.1038/s41541-021-00378-5

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