Carbamylation of elastic fibers is a molecular substratum of aortic stiffness

Because of their long lifespan, matrix proteins of the vascular wall, such as elastin, are subjected to molecular aging characterized by non-enzymatic post-translational modifications, like carbamylation which results from the binding of cyanate (mainly derived from the dissociation of urea) to prot...

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Detalles Bibliográficos
Autores principales: Doué, Manon, Okwieka, Anaïs, Berquand, Alexandre, Gorisse, Laëtitia, Maurice, Pascal, Velard, Frédéric, Terryn, Christine, Molinari, Michaël, Duca, Laurent, Piétrement, Christine, Gillery, Philippe, Jaisson, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426361/
https://www.ncbi.nlm.nih.gov/pubmed/34497312
http://dx.doi.org/10.1038/s41598-021-97293-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426361/
https://www.ncbi.nlm.nih.gov/pubmed/34497312
http://dx.doi.org/10.1038/s41598-021-97293-5

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