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Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer

Metastasis is the main cause of death in patients with advanced lung cancer. The exosomes released by cancer cells create tumor microenvironment, and then accelerate tumor metastasis. Cancer-derived exosomes are considered to be the main driving force for metastasis niche formation at foreign sites,...

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Detalles Bibliográficos
Autores principales: Ma, Zijian, Wei, Ke, Yang, Fengming, Guo, Zizhang, Pan, Chunfeng, He, Yaozhou, Wang, Jun, Li, Zhihua, Chen, Liang, Chen, YiJiang, Xia, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426367/
https://www.ncbi.nlm.nih.gov/pubmed/34497265
http://dx.doi.org/10.1038/s41419-021-04037-4