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METTL3 promotes the initiation and metastasis of ovarian cancer by inhibiting CCNG2 expression via promoting the maturation of pri-microRNA-1246

Ovarian cancer is a common gynecological malignant tumor with a high mortality rate and poor prognosis. There is inadequate knowledge of the molecular mechanisms underlying ovarian cancer. We examined the expression of methyltransferase-like 3 (METTL3) in tumor specimens using RT-qPCR, immunohistoch...

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Detalles Bibliográficos
Autores principales: Bi, Xuehan, Lv, Xiao, Liu, Dajiang, Guo, Hongtao, Yao, Guang, Wang, Lijuan, Liang, Xiaolei, Yang, Yongxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426370/
https://www.ncbi.nlm.nih.gov/pubmed/34497267
http://dx.doi.org/10.1038/s41420-021-00600-2