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Genetic polymorphism of CYP2C19 and subcortical variability in the human adult brain

Pharmacogenetic studies have shown involvement of cytochrome P450 enzymes in the metabolism of psychotropic drugs. However, expression and activity on endogenous substrates in the brain may underlie a constitutive role of these enzymes beyond drug metabolism. CYP2C19, which is expressed in the human...

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Detalles Bibliográficos
Autores principales: Stingl, Julia C., Scholl, Catharina, Bosch, Julia E., Viviani, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426391/
https://www.ncbi.nlm.nih.gov/pubmed/34497262
http://dx.doi.org/10.1038/s41398-021-01591-5