Cargando…
Genetic polymorphism of CYP2C19 and subcortical variability in the human adult brain
Pharmacogenetic studies have shown involvement of cytochrome P450 enzymes in the metabolism of psychotropic drugs. However, expression and activity on endogenous substrates in the brain may underlie a constitutive role of these enzymes beyond drug metabolism. CYP2C19, which is expressed in the human...
Autores principales: | Stingl, Julia C., Scholl, Catharina, Bosch, Julia E., Viviani, Roberto |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426391/ https://www.ncbi.nlm.nih.gov/pubmed/34497262 http://dx.doi.org/10.1038/s41398-021-01591-5 |
Ejemplares similares
-
Effects of genetic variability of CYP2D6 on neural substrates of sustained attention during on-task activity
por: Viviani, Roberto, et al.
Publicado: (2020) -
Pharmacogenetic Dose Modeling Based on CYP2C19 Allelic Phenotypes
por: Stingl, Julia Carolin, et al.
Publicado: (2022) -
Signals of anticipation of reward and of mean reward rates in the human brain
por: Viviani, Roberto, et al.
Publicado: (2020) -
A Digital Atlas of Middle to Large Brain Vessels and Their Relation to Cortical and Subcortical Structures
por: Viviani, Roberto
Publicado: (2016) -
CYP2D6 in the Brain: Potential Impact on Adverse Drug Reactions in the Central Nervous System—Results From the ADRED Study
por: Just, Katja S., et al.
Publicado: (2021)