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Sitagliptin attenuates arterial calcification by downregulating oxidative stress-induced receptor for advanced glycation end products in LDLR knockout mice

Diabetes is a complex disease characterized by hyperglycemia, dyslipidemia, and insulin resistance. Plasma advanced glycation end products (AGEs) activated the receptor for advanced glycation end products (RAGE) and the activation of RAGE is implicated to be the pathogenesis of type 2 diabetic melli...

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Detalles Bibliográficos
Autores principales: Lin, Chih-Pei, Huang, Po-Hsun, Chen, Chi-Yu, Wu, Meng-Yu, Chen, Jia-Shiong, Chen, Jaw-Wen, Lin, Shing-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426400/
https://www.ncbi.nlm.nih.gov/pubmed/34497344
http://dx.doi.org/10.1038/s41598-021-97361-w