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Pharmacological Inhibition of STAT6 Ameliorates Myeloid Fibroblast Activation and Alternative Macrophage Polarization in Renal Fibrosis

A hallmark of chronic kidney disease is renal fibrosis, which can result in progressive loss of kidney function. Currently, there is no effective therapy for renal fibrosis. Therefore, there is an urgent need to identify potential drug targets for renal fibrosis. In this study, we examined the effec...

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Detalles Bibliográficos
Autores principales: Jiao, Baihai, An, Changlong, Tran, Melanie, Du, Hao, Wang, Penghua, Zhou, Dong, Wang, Yanlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426438/
https://www.ncbi.nlm.nih.gov/pubmed/34512669
http://dx.doi.org/10.3389/fimmu.2021.735014