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Microglial ASD-related genes are involved in oligodendrocyte differentiation

Autism spectrum disorders (ASD) are associated with mutations of chromodomain-helicase DNA-binding protein 8 (Chd8) and tuberous sclerosis complex 2 (Tsc2). Although these ASD-related genes are detected in glial cells such as microglia, the effect of Chd8 or Tsc2 deficiency on microglial functions a...

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Detalles Bibliográficos
Autores principales: Takanezawa, Yuta, Tanabe, Shogo, Kato, Daiki, Ozeki, Rie, Komoda, Masayo, Suzuki, Tatsunori, Baba, Hiroko, Muramatsu, Rieko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426463/
https://www.ncbi.nlm.nih.gov/pubmed/34497307
http://dx.doi.org/10.1038/s41598-021-97257-9