Making use of transcription factor enrichment to identify functional microRNA-regulons

microRNAs (miRNAs) are important modulators of messenger RNA stability and translation, controlling wide gene networks. Albeit generally modest on individual targets, the regulatory effect of miRNAs translates into meaningful pathway modulation through concurrent targeting of regulons with functiona...

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Detalles Bibliográficos
Autores principales: Prompsy, Pacôme B., Toubia, John, Gearing, Linden J., Knight, Randle L., Forster, Samuel C., Bracken, Cameron P., Gantier, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426468/
https://www.ncbi.nlm.nih.gov/pubmed/34522293
http://dx.doi.org/10.1016/j.csbj.2021.08.032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426468/
https://www.ncbi.nlm.nih.gov/pubmed/34522293
http://dx.doi.org/10.1016/j.csbj.2021.08.032

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