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Making use of transcription factor enrichment to identify functional microRNA-regulons
microRNAs (miRNAs) are important modulators of messenger RNA stability and translation, controlling wide gene networks. Albeit generally modest on individual targets, the regulatory effect of miRNAs translates into meaningful pathway modulation through concurrent targeting of regulons with functiona...
Autores principales: | Prompsy, Pacôme B., Toubia, John, Gearing, Linden J., Knight, Randle L., Forster, Samuel C., Bracken, Cameron P., Gantier, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426468/ https://www.ncbi.nlm.nih.gov/pubmed/34522293 http://dx.doi.org/10.1016/j.csbj.2021.08.032 |
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