Optimized pharmacological control over the AAV-Gene-Switch vector for regulable gene therapy

Gene therapy in its current design is an irreversible process. It cannot be stopped in case of unwanted side effects, nor can expression levels of therapeutics be adjusted to individual patient’s needs. Thus, the Gene-Switch (GS) system for pharmacologically regulable neurotrophic factor expression...

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Detalles Bibliográficos
Autores principales: Cheng, Shi, van Gaalen, Marcel M., Bähr, Mathias, Garea-Rodriguez, Enrique, Kügler, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426472/
https://www.ncbi.nlm.nih.gov/pubmed/34552998
http://dx.doi.org/10.1016/j.omtm.2021.07.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426472/
https://www.ncbi.nlm.nih.gov/pubmed/34552998
http://dx.doi.org/10.1016/j.omtm.2021.07.007

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