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Specific gene expression in unmyelinated dorsal root ganglion neurons in nonhuman primates by intra-nerve injection of AAV 6 vector

Adeno-associated virus 6 (AAV6) has been proposed as a potential vector candidate for specific gene expression in pain-related dorsal root ganglion (DRG) neurons, but this has not been confirmed in nonhuman primates. The aim of our study was to analyze the transduction efficiency and target specific...

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Detalles Bibliográficos
Autores principales: Kudo, Moeko, Wupuer, Sidikejiang, Fujiwara, Maki, Saito, Yuko, Kubota, Shinji, Inoue, Ken-ichi, Takada, Masahiko, Seki, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426475/
https://www.ncbi.nlm.nih.gov/pubmed/34552999
http://dx.doi.org/10.1016/j.omtm.2021.07.009