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Toward Development of Neuron Specific Transduction After Systemic Delivery of Viral Vectors
Widespread transduction of the CNS with a single, non-invasive systemic injection of adeno-associated virus is now possible due to the creation of blood-brain barrier-permeable capsids. However, as these capsids are mutants of AAV9, they do not have specific neuronal tropism. Therefore, it is necess...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426581/ https://www.ncbi.nlm.nih.gov/pubmed/34512509 http://dx.doi.org/10.3389/fneur.2021.685802 |