SAMHD1 Phosphorylation at T592 Regulates Cellular Localization and S-phase Progression

SAMHD1 activity is regulated by a network of mechanisms including phosphorylation, oxidation, oligomerization, and others. Significant questions remain about the effects of phosphorylation on SAMHD1 function and activity. We investigated the effects of a SAMHD1 T592E phosphorylation mimic on its cel...

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Detalles Bibliográficos
Autores principales: Batalis, Stephanie, Rogers, LeAnn C., Hemphill, Wayne O., Mauney, Christopher H., Ornelles, David A., Hollis, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426622/
https://www.ncbi.nlm.nih.gov/pubmed/34513928
http://dx.doi.org/10.3389/fmolb.2021.724870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426622/
https://www.ncbi.nlm.nih.gov/pubmed/34513928
http://dx.doi.org/10.3389/fmolb.2021.724870

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