Exploring the Druggability of Conserved RNA Regulatory Elements in the SARS‐CoV‐2 Genome

SARS‐CoV‐2 contains a positive single‐stranded RNA genome of approximately 30 000 nucleotides. Within this genome, 15 RNA elements were identified as conserved between SARS‐CoV and SARS‐CoV‐2. By nuclear magnetic resonance (NMR) spectroscopy, we previously determined that these elements fold indepen...

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Detalles Bibliográficos
Autores principales: Sreeramulu, Sridhar, Richter, Christian, Berg, Hannes, Wirtz Martin, Maria A., Ceylan, Betül, Matzel, Tobias, Adam, Jennifer, Altincekic, Nadide, Azzaoui, Kamal, Bains, Jasleen Kaur, Blommers, Marcel J. J., Ferner, Jan, Fürtig, Boris, Göbel, Michael, Grün, J. Tassilo, Hengesbach, Martin, Hohmann, Katharina F., Hymon, Daniel, Knezic, Bozana, Martins, Jason N., Mertinkus, Klara R., Niesteruk, Anna, Peter, Stephen A., Pyper, Dennis J., Qureshi, Nusrat S., Scheffer, Ute, Schlundt, Andreas, Schnieders, Robbin, Stirnal, Elke, Sudakov, Alexey, Tröster, Alix, Vögele, Jennifer, Wacker, Anna, Weigand, Julia E., Wirmer‐Bartoschek, Julia, Wöhnert, Jens, Schwalbe, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426693/
https://www.ncbi.nlm.nih.gov/pubmed/34161644
http://dx.doi.org/10.1002/anie.202103693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426693/
https://www.ncbi.nlm.nih.gov/pubmed/34161644
http://dx.doi.org/10.1002/anie.202103693

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