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Enzymatic Assays to Explore Viral mRNA Capping Machinery

In eukaryotes, mRNA is modified by the addition of the 7‐methylguanosine (m(7)G) 5′ cap to protect mRNA from premature degradation, thereby enhancing translation and enabling differentiation between self (endogenous) and non‐self RNAs (e. g., viral ones). Viruses often develop their own mRNA capping...

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Detalles Bibliográficos
Autores principales: Kasprzyk, Renata, Jemielity, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426721/
https://www.ncbi.nlm.nih.gov/pubmed/34291555
http://dx.doi.org/10.1002/cbic.202100291