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A glycosaminoglycan microarray identifies the binding of SARS‐CoV‐2 spike protein to chondroitin sulfate E

Heparan sulfate (HS), a sulfated glycosaminoglycan (GAG), was reported to be a necessary host attachment factor that promotes SARS‐CoV‐2 infection. In this study, we developed GAG microarrays based on fluorescence detection for high‐sensitivity screening of the GAG‐binding specificity of proteins an...

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Detalles Bibliográficos
Autores principales: Watanabe, Tomoko, Takeda, Ko, Hiemori, Keiko, Minamisawa, Toshikazu, Tateno, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427098/
https://www.ncbi.nlm.nih.gov/pubmed/34375459
http://dx.doi.org/10.1002/1873-3468.14173