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cGAS–STING and MyD88 Pathways Synergize in Ly6C(hi) Monocyte to Promote Streptococcus pneumoniae-Induced Late-Stage Lung IFNγ Production
The cyclic GMP–AMP synthase–stimulator of interferon genes (cGAS–STING) pathway senses DNA and induces type I interferon (IFN) production. Whether and how the STING pathway crosstalk to other innate immune pathways during pathogen infection, however, remains unclear. Here, we showed that STING was n...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427188/ https://www.ncbi.nlm.nih.gov/pubmed/34512626 http://dx.doi.org/10.3389/fimmu.2021.699702 |