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PGC-1α promotes mitochondrial respiration and biogenesis during the differentiation of hiPSCs into cardiomyocytes

Although it is widely accepted that human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are readily available, robustly reproducible, and physiologically appropriate human cells for clinical applications and research in the cardiovascular field, hiPSC-CMs cultured in vitro retain...

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Detalles Bibliográficos
Autores principales: Zhou, Qin, Xu, Hao, Yan, Liang, Ye, Liang, Zhang, Xinyuan, Tan, Bin, Yi, Qin, Tian, Jie, Zhu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427271/
https://www.ncbi.nlm.nih.gov/pubmed/34522716
http://dx.doi.org/10.1016/j.gendis.2020.12.006