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CYP450 Genotype—Phenotype Concordance Using the Geneva Micrococktail in a Clinical Setting
Pharmacokinetic variability is a major source of differences in drug response and can be due to genetic variants and/or drug-drug interactions. Cytochromes P450 are among the most studied enzymes from a pharmacokinetic point of view. Their activity can be measured by phenotyping, and/or predicted by...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427306/ https://www.ncbi.nlm.nih.gov/pubmed/34512355 http://dx.doi.org/10.3389/fphar.2021.730637 |