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CYP450 Genotype—Phenotype Concordance Using the Geneva Micrococktail in a Clinical Setting

Pharmacokinetic variability is a major source of differences in drug response and can be due to genetic variants and/or drug-drug interactions. Cytochromes P450 are among the most studied enzymes from a pharmacokinetic point of view. Their activity can be measured by phenotyping, and/or predicted by...

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Detalles Bibliográficos
Autores principales: Ing Lorenzini, Kuntheavy, Desmeules, Jules, Rollason, Victoria, Bertin, Stéphane, Besson, Marie, Daali, Youssef, Samer, Caroline F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427306/
https://www.ncbi.nlm.nih.gov/pubmed/34512355
http://dx.doi.org/10.3389/fphar.2021.730637