Identification of novel inhibitory metabolites and impact verification on growth and protein synthesis in mammalian cells

Mammalian cells consume large amount of nutrients during growth and production. However, endogenous metabolic inefficiencies often prevent cells to fully utilize nutrients to support growth and protein production. Instead, significant fraction of fed nutrients is diverted into extracellular accumula...

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Detalles Bibliográficos
Autores principales: Kuang, Bingyu, Dhara, Venkata Gayatri, Hoang, Duc, Jenkins, Jack, Ladiwala, Pranay, Tan, Yanglan, Shaffer, Scott A., Galbraith, Shaun C., Betenbaugh, Michael J., Yoon, Seongkyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427323/
https://www.ncbi.nlm.nih.gov/pubmed/34522610
http://dx.doi.org/10.1016/j.mec.2021.e00182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427323/
https://www.ncbi.nlm.nih.gov/pubmed/34522610
http://dx.doi.org/10.1016/j.mec.2021.e00182

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