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Identification of novel inhibitory metabolites and impact verification on growth and protein synthesis in mammalian cells
Mammalian cells consume large amount of nutrients during growth and production. However, endogenous metabolic inefficiencies often prevent cells to fully utilize nutrients to support growth and protein production. Instead, significant fraction of fed nutrients is diverted into extracellular accumula...
Autores principales: | Kuang, Bingyu, Dhara, Venkata Gayatri, Hoang, Duc, Jenkins, Jack, Ladiwala, Pranay, Tan, Yanglan, Shaffer, Scott A., Galbraith, Shaun C., Betenbaugh, Michael J., Yoon, Seongkyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427323/ https://www.ncbi.nlm.nih.gov/pubmed/34522610 http://dx.doi.org/10.1016/j.mec.2021.e00182 |
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