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Structure-function analysis of MmpL7-mediated lipid transport in mycobacteria

Mycobacterial membrane protein Large (MmpL7) is a Resistance-Nodulation-Division (RND) family transporter required for the export of the virulence lipid, phthiocerol dimycocerosate (PDIM), in Mycobacterium tuberculosis. Using a null mutant of the related, vaccine strain Mycobacterium bovis BCG, we s...

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Detalles Bibliográficos
Autores principales: Moolla, Nabiela, Bailo, Rebeca, Marshall, Robert, Bavro, Vassiliy N., Bhatt, Apoorva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427324/
https://www.ncbi.nlm.nih.gov/pubmed/34522829
http://dx.doi.org/10.1016/j.tcsw.2021.100062