High-Mobility Group A1 Promotes Cardiac Fibrosis by Upregulating FOXO1 in Fibroblasts

High-mobility group A1 (HMGA1) acts as a transcription factor in several cardiovascular diseases. However, the implications of HMGA1 in cardiac fibrosis remain unknown. Here, we investigated the impact of HMGA1 on cardiac fibrosis. A mouse cardiac fibrosis model was constructed via subcutaneous inje...

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Detalles Bibliográficos
Autores principales: Xie, Qingwen, Yao, Qi, Hu, Tongtong, Cai, Zhulan, Zhao, Jinhua, Yuan, Yuan, Wu, Qing Qing, Tang, Qi-zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427498/
https://www.ncbi.nlm.nih.gov/pubmed/34513822
http://dx.doi.org/10.3389/fcell.2021.666422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427498/
https://www.ncbi.nlm.nih.gov/pubmed/34513822
http://dx.doi.org/10.3389/fcell.2021.666422

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