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High-Mobility Group A1 Promotes Cardiac Fibrosis by Upregulating FOXO1 in Fibroblasts
High-mobility group A1 (HMGA1) acts as a transcription factor in several cardiovascular diseases. However, the implications of HMGA1 in cardiac fibrosis remain unknown. Here, we investigated the impact of HMGA1 on cardiac fibrosis. A mouse cardiac fibrosis model was constructed via subcutaneous inje...
Autores principales: | Xie, Qingwen, Yao, Qi, Hu, Tongtong, Cai, Zhulan, Zhao, Jinhua, Yuan, Yuan, Wu, Qing Qing, Tang, Qi-zhu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427498/ https://www.ncbi.nlm.nih.gov/pubmed/34513822 http://dx.doi.org/10.3389/fcell.2021.666422 |
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