Exploring Ligand Binding to Calcitonin Gene-Related Peptide Receptors

Class B1 G protein-coupled receptors (GPCRs) are important targets for many diseases, including cancer, diabetes, and heart disease. All the approved drugs for this receptor family are peptides that mimic the endogenous activating hormones. An understanding of how agonists bind and activate class B1...

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Detalles Bibliográficos
Autores principales: Deganutti, Giuseppe, Atanasio, Silvia, Rujan, Roxana-Maria, Sexton, Patrick M., Wootten, Denise, Reynolds, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427520/
https://www.ncbi.nlm.nih.gov/pubmed/34513925
http://dx.doi.org/10.3389/fmolb.2021.720561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427520/
https://www.ncbi.nlm.nih.gov/pubmed/34513925
http://dx.doi.org/10.3389/fmolb.2021.720561

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