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A Central Role for Atg5 in Microbiota-Dependent Foxp3(+) RORγt(+) Treg Cell Preservation to Maintain Intestinal Immune Homeostasis

Autophagy is an evolutionary conserved catabolic pathway that ensures the degradation of intracellular components. The autophagic pathway is regulated by autophagy-related (Atg) proteins that govern formation of double-membraned vesicles called autophagosomes. Autophagy deficiency in regulatory T (T...

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Detalles Bibliográficos
Autores principales: Plaza-Sirvent, Carlos, Zhao, Bei, Bronietzki, Alisha W., Pils, Marina C., Tafrishi, Neda, Schuster, Marc, Strowig, Till, Schmitz, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427596/
https://www.ncbi.nlm.nih.gov/pubmed/34512629
http://dx.doi.org/10.3389/fimmu.2021.705436