Minimalistic peptidic scaffolds harbouring an artificial carbene-containing amino acid modulate reductase activity

Inspired by the boom of new artificial metalloenzymes, we developed an Fmoc-protected histidinium salt (Hum) as N-heterocyclic carbene precursor. Hum was placed via solid-phase peptide synthesis into short 7-mer peptides. Upon iridation, the metallo-peptidic construct displayed activity in catalytic...

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Detalles Bibliográficos
Autores principales: Lenzen, Karst, Planchestainer, Matteo, Feller, Isabelle, Padrosa, David Roura, Paradisi, Francesca, Albrecht, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427656/
https://www.ncbi.nlm.nih.gov/pubmed/34498652
http://dx.doi.org/10.1039/d1cc03158a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427656/
https://www.ncbi.nlm.nih.gov/pubmed/34498652
http://dx.doi.org/10.1039/d1cc03158a

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