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Angiopoietins as Potential Targets in Management of Retinal Disease

The Ang/Tie2 pathway complements VEGF-mediated activity in retinal vascular diseases such as DME, AMD, and RVO by decreasing vascular integrity, increasing neovascularization, and increasing inflammatory signaling. Faricimab is a bispecific antibody that has been developed as an inhibitor of both VE...

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Detalles Bibliográficos
Autores principales: Khanani, Arshad M, Russell, Matthew W, Aziz, Aamir A, Danzig, Carl J, Weng, Christina Y, Eichenbaum, David A, Singh, Rishi P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427682/
https://www.ncbi.nlm.nih.gov/pubmed/34511878
http://dx.doi.org/10.2147/OPTH.S231801