METTL14 promotes glomerular endothelial cell injury and diabetic nephropathy via m6A modification of α-klotho

BACKGROUND: N6-Methyladenosine (m6A) modification has been implicated in many bioprocesses. However, its functions in diabetic nephropathy (DN) have not been determined. Here, we investigated the role of METTL14, a key component of the m6A methyltransferase complex, in DN. METHODS: The expression of...

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Detalles Bibliográficos
Autores principales: Li, Manna, Deng, Le, Xu, Gaosi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427885/
https://www.ncbi.nlm.nih.gov/pubmed/34503454
http://dx.doi.org/10.1186/s10020-021-00365-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427885/
https://www.ncbi.nlm.nih.gov/pubmed/34503454
http://dx.doi.org/10.1186/s10020-021-00365-5

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