Thymoquinone and Costunolide Induce Apoptosis of Both Proliferative and Doxorubicin-Induced-Senescent Colon and Breast Cancer Cells

Doxorubicin (Dox) induces senescence in numerous cancer cell types, but these senescent cancer cells relapse again if they are not eliminated. On this principle, we investigated the apoptotic effect of thymoquinone (TQ), the active ingredient of Nigella sativa seeds and costunolide (COS), the active...

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Detalles Bibliográficos
Autores principales: El-Far, Ali H, Godugu, Kavitha, Noreldin, Ahmed E., Saddiq, Amna A., Almaghrabi, Omar A., Al Jaouni, Soad K., Mousa, Shaker A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427913/
https://www.ncbi.nlm.nih.gov/pubmed/34490824
http://dx.doi.org/10.1177/15347354211035450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427913/
https://www.ncbi.nlm.nih.gov/pubmed/34490824
http://dx.doi.org/10.1177/15347354211035450

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