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Thymoquinone and Costunolide Induce Apoptosis of Both Proliferative and Doxorubicin-Induced-Senescent Colon and Breast Cancer Cells
Doxorubicin (Dox) induces senescence in numerous cancer cell types, but these senescent cancer cells relapse again if they are not eliminated. On this principle, we investigated the apoptotic effect of thymoquinone (TQ), the active ingredient of Nigella sativa seeds and costunolide (COS), the active...
Autores principales: | El-Far, Ali H, Godugu, Kavitha, Noreldin, Ahmed E., Saddiq, Amna A., Almaghrabi, Omar A., Al Jaouni, Soad K., Mousa, Shaker A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427913/ https://www.ncbi.nlm.nih.gov/pubmed/34490824 http://dx.doi.org/10.1177/15347354211035450 |
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