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Collusion of α-Synuclein and Aβ aggravating co-morbidities in a novel prion-type mouse model
BACKGROUND: The misfolding of host-encoded proteins into pathological prion conformations is a defining characteristic of many neurodegenerative disorders, including Alzheimer’s disease, Parkinson’s disease, and Lewy body dementia. A current area of intense study is the way in which the pathological...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427941/ https://www.ncbi.nlm.nih.gov/pubmed/34503546 http://dx.doi.org/10.1186/s13024-021-00486-9 |