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Collusion of α-Synuclein and Aβ aggravating co-morbidities in a novel prion-type mouse model

BACKGROUND: The misfolding of host-encoded proteins into pathological prion conformations is a defining characteristic of many neurodegenerative disorders, including Alzheimer’s disease, Parkinson’s disease, and Lewy body dementia. A current area of intense study is the way in which the pathological...

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Detalles Bibliográficos
Autores principales:	Lloyd, Grace M., Dhillon, Jess-Karan S., Gorion, Kimberly-Marie M., Riffe, Cara, Fromholt, Susan E., Xia, Yuxing, Giasson, Benoit I., Borchelt, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427941/ https://www.ncbi.nlm.nih.gov/pubmed/34503546 http://dx.doi.org/10.1186/s13024-021-00486-9

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