Regulation of the HTRA2 Protease Activity by an Inhibitory Antibody-Derived Peptide Ligand and the Influence on HTRA2-Specific Protein Interaction Networks in Retinal Tissues

The mitochondrial serine protease HTRA2 has many versatile biological functions ranging from being an important regulator of apoptosis to being an essential component for neuronal cell survival and mitochondrial homeostasis. Loss of HTRA2 protease function is known to cause neurodegeneration, wherea...

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Detalles Bibliográficos
Autores principales: Schmelter, Carsten, Fomo, Kristian Nzogang, Perumal, Natarajan, Pfeiffer, Norbert, Grus, Franz H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427973/
https://www.ncbi.nlm.nih.gov/pubmed/34440217
http://dx.doi.org/10.3390/biomedicines9081013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427973/
https://www.ncbi.nlm.nih.gov/pubmed/34440217
http://dx.doi.org/10.3390/biomedicines9081013

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