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Chaperone-mediated autophagy sustains hematopoietic stem cell function

Activation of mostly quiescent hematopoietic stem cells (HSC) is a prerequisite for life-long blood production(1, 2). This process requires major molecular adaptations to meet the regulatory and metabolic requirements for cell division(3–8). The mechanisms governing cellular reprograming upon stem c...

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Detalles Bibliográficos
Autores principales: Dong, S, Wang, Q, Kao, YR, Diaz, A, Tasset, I, Kaushik, S, Thiruthuvanathan, V, Zintiridou, A, Nieves, E, Dzieciatkowska, M, Reisz, JA, Gavathiotis, E, D’Alessandro, A, Will, B, Cuervo, AM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428053/
https://www.ncbi.nlm.nih.gov/pubmed/33442062
http://dx.doi.org/10.1038/s41586-020-03129-z