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Chaperone-mediated autophagy sustains hematopoietic stem cell function
Activation of mostly quiescent hematopoietic stem cells (HSC) is a prerequisite for life-long blood production(1, 2). This process requires major molecular adaptations to meet the regulatory and metabolic requirements for cell division(3–8). The mechanisms governing cellular reprograming upon stem c...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428053/ https://www.ncbi.nlm.nih.gov/pubmed/33442062 http://dx.doi.org/10.1038/s41586-020-03129-z |