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Targeting β-cell dedifferentiation and transdifferentiation: opportunities and challenges
The most distinctive pathological characteristics of diabetes mellitus induced by various stressors or immune-mediated injuries are reductions of pancreatic islet β-cell populations and activity. Existing treatment strategies cannot slow disease progression; consequently, research to genetically eng...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Bioscientifica Ltd
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428079/ https://www.ncbi.nlm.nih.gov/pubmed/34289444 http://dx.doi.org/10.1530/EC-21-0260 |