Homology-directed gene-editing approaches for hematopoietic stem and progenitor cell gene therapy

The advent of next-generation genome engineering tools like CRISPR-Cas9 has transformed the field of gene therapy, rendering targeted treatment for several incurable diseases. Hematopoietic stem and progenitor cells (HSPCs) continue to be the ideal target cells for gene manipulation due to their lon...

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Detalles Bibliográficos
Autores principales: Azhagiri, Manoj Kumar K., Babu, Prathibha, Venkatesan, Vigneshwaran, Thangavel, Saravanabhavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428126/
https://www.ncbi.nlm.nih.gov/pubmed/34503562
http://dx.doi.org/10.1186/s13287-021-02565-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428126/
https://www.ncbi.nlm.nih.gov/pubmed/34503562
http://dx.doi.org/10.1186/s13287-021-02565-6

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