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Celastrol Niosome Hydrogel Has Anti-Inflammatory Effect on Skin Keratinocytes and Circulation without Systemic Drug Exposure in Psoriasis Mice

PURPOSE: Psoriasis is an inflammatory skin disease, where keratinocytes play pivotal roles in its pathogenesis. We prepared Celastrol Noisome hydrogel (Cel Nio gel) for the treatment of psoriasis and aimed to study its target site as well as the mechanism. METHODS: Cel Nio was fabricated with thin-f...

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Detalles Bibliográficos
Autores principales: Qiu, Fen, Xi, Long, Chen, Shengshuang, Zhao, Yonghua, Wang, Zhenping, Zheng, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428181/
https://www.ncbi.nlm.nih.gov/pubmed/34511913
http://dx.doi.org/10.2147/IJN.S323208