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Targeting DNA Damage Repair Mechanisms in Pancreas Cancer

SIMPLE SUMMARY: Pancreatic cancer is a devastating malignant disease with a dismal prognosis and limited treatment options. Around 14% of pancreatic cancers harbour mutations in specific genes that are important to ensure appropriate DNA repair after damage, like the BRCA 1 and 2 genes. Recently, wi...

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Detalles Bibliográficos
Autores principales: Perkhofer, Lukas, Golan, Talia, Cuyle, Pieter-Jan, Matysiak-Budnik, Tamara, Van Laethem, Jean-Luc, Macarulla, Teresa, Cauchin, Estelle, Kleger, Alexander, Beutel, Alica K., Gout, Johann, Stenzinger, Albrecht, Van Cutsem, Eric, Bellmunt, Joaquim, Hammel, Pascal, O’Reilly, Eileen M., Seufferlein, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428219/
https://www.ncbi.nlm.nih.gov/pubmed/34503069
http://dx.doi.org/10.3390/cancers13174259