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A highly effective and self-transmissible CRISPR antimicrobial for elimination of target plasmids without antibiotic selection

The use of CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR associated protein) for sequence-specific elimination of bacteria or resistance genes is a powerful tool for combating antibiotic resistance. However, this approach requires efficient delivery of CRISPR/Cas DNA c...

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Detalles Bibliográficos
Autores principales: Wongpayak, Panjaporn, Meesungnoen, Orapan, Saejang, Somchai, Subsoontorn, Pakpoom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428258/
https://www.ncbi.nlm.nih.gov/pubmed/34567840
http://dx.doi.org/10.7717/peerj.11996