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A highly effective and self-transmissible CRISPR antimicrobial for elimination of target plasmids without antibiotic selection
The use of CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR associated protein) for sequence-specific elimination of bacteria or resistance genes is a powerful tool for combating antibiotic resistance. However, this approach requires efficient delivery of CRISPR/Cas DNA c...
Autores principales: | Wongpayak, Panjaporn, Meesungnoen, Orapan, Saejang, Somchai, Subsoontorn, Pakpoom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428258/ https://www.ncbi.nlm.nih.gov/pubmed/34567840 http://dx.doi.org/10.7717/peerj.11996 |
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