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CPT1A and fatty acid β-oxidation are essential for tumor cell growth and survival in hormone receptor-positive breast cancer

Chromosome 11q13-14 amplification is a defining feature of high-risk hormone receptor-positive (HR+) breast cancer; however, the mechanism(s) by which this amplicon contributes to breast tumorigenesis remains unclear. In the current study, proteogenomic analyses of >3000 breast tumors from the TC...

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Detalles Bibliográficos
Autores principales: Jariwala, Nidhi, Mehta, Gaurav A, Bhatt, Vrushank, Hussein, Shaimaa, Parker, Kimberly A, Yunus, Neha, Parker, Joel S, Guo, Jessie Yanxiang, Gatza, Michael L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8428294/
https://www.ncbi.nlm.nih.gov/pubmed/34514415
http://dx.doi.org/10.1093/narcan/zcab035